Business address

Institute for Ophthalmic Research
University of Tübingen
Elfriede-Aulhorn-Strasse 7
D-72076 Tübingen,
Germany

Phone: +49 (0)7071 29-84947
Fax: +49 (0)7071 29-5777
E-mail: ellen.kilger@uni-tuebingen.de

1. Merle, D. A., Provenzano, F., Jarboui, M. A., Kilger, E., Clark, S. J., Deleidi, M., Armento, A., and Ueffing, M. (2021) mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells. Antioxidants (Basel) 10
2. Armento, A., Schmidt, T. L., Sonntag, I., Merle, D. A., Jarboui, M. A., Kilger, E., Clark, S. J., and Ueffing, M. (2021) CFH Loss in Human RPE Cells Leads to Inflammation and Complement System Dysregulation via the NF-kappaB Pathway. Int J Mol Sci 22
3. Armento, A., Murali, A., Marzi, J., Almansa-Garcia, A. C., Arango-Gonzalez, B., Kilger, E., Clark, S. J., Schenke-Layland, K., Ramlogan-Steel, C. A., Steel, J. C., and Ueffing, M. (2021) Complement Factor H Loss in RPE Cells Causes Retinal Degeneration in a Human RPE-Porcine Retinal Explant Co-Culture Model. Biomolecules 11
4. Armento, A., Honisch, S., Panagiotakopoulou, V., Sonntag, I., Jacob, A., Bolz, S., Kilger, E., Deleidi, M., Clark, S., and Ueffing, M. (2020) Loss of Complement Factor H impairs antioxidant capacity and energy metabolism of human RPE cells. Sci Rep 10, 10320
5. Kilger, E., Buehler, A., Woelfing, H., Kumar, S., Kaeser, S. A., Nagarathinam, A., Walter, J., Jucker, M., and Coomaraswamy, J. (2011) BRI2 protein regulates beta-amyloid degradation by increasing levels of secreted insulin-degrading enzyme (IDE). J Biol Chem 286, 37446-37457
6. Coomaraswamy, J., Kilger, E., Wolfing, H., Schafer, C., Kaeser, S. A., Wegenast-Braun, B. M., Hefendehl, J. K., Wolburg, H., Mazzella, M., Ghiso, J., Goedert, M., Akiyama, H., Garcia-Sierra, F., Wolfer, D. P., Mathews, P. M., and Jucker, M. (2010) Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease. Proc Natl Acad Sci U S A 107, 7969-7974
7. Kaeser, S. A., Herzig, M. C., Coomaraswamy, J., Kilger, E., Selenica, M. L., Winkler, D. T., Staufenbiel, M., Levy, E., Grubb, A., and Jucker, M. (2007) Cystatin C modulates cerebral beta-amyloidosis. Nature genetics 39, 1437-1439
8. Hamid, R., Kilger, E., Willem, M., Vassallo, N., Kostka, M., Bornhovd, C., Reichert, A. S., Kretzschmar, H. A., Haass, C., and Herms, J. (2007) Amyloid precursor protein intracellular domain modulates cellular calcium homeostasis and ATP content. J Neurochem 102, 1264-1275
9. Eisele, Y. S., Baumann, M., Klebl, B., Nordhammer, C., Jucker, M., and Kilger, E. (2007) Gleevec increases levels of the amyloid precursor protein intracellular domain and of the amyloid-beta degrading enzyme neprilysin. Molecular biology of the cell 18, 3591-3600
10. Meyer-Luehmann, M., Coomaraswamy, J., Bolmont, T., Kaeser, S., Schaefer, C., Kilger, E., Neuenschwander, A., Abramowski, D., Frey, P., Jaton, A. L., Vigouret, J. M., Paganetti, P., Walsh, D. M., Mathews, P. M., Ghiso, J., Staufenbiel, M., Walker, L. C., and Jucker, M. (2006) Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host. Science 313, 1781-1784
11. Dirmeier, U., Hoffmann, R., Kilger, E., Schultheiss, U., Briseno, C., Gires, O., Kieser, A., Eick, D., Sugden, B., and Hammerschmidt, W. (2005) Latent membrane protein 1 of Epstein-Barr virus coordinately regulates proliferation with control of apoptosis. Oncogene 24, 1711-1717
12. Dirmeier, U., Neuhierl, B., Kilger, E., Reisbach, G., Sandberg, M. L., and Hammerschmidt, W. (2003) Latent membrane protein 1 is critical for efficient growth transformation of human B cells by epstein-barr virus. Cancer Res 63, 2982-2989
13. Kilger, E., and Hammerschmidt, W. (2001) Genetic analysis and gene expression with mini-Epstein-Barr virus plasmids. Methods Mol Biol 174, 23-35
14. Kilger, E., Pecher, G., Schwenk, A., and Hammerschmidt, W. (1999) Expression of mucin (MUC-1) from a mini-Epstein-Barr virus in immortalized B-cells to generate tumor antigen specific cytotoxic T cells. J Gene Med 1, 84-92
15. Gires, O., Kohlhuber, F., Kilger, E., Baumann, M., Kieser, A., Kaiser, C., Zeidler, R., Scheffer, B., Ueffing, M., and Hammerschmidt, W. (1999) Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins. EMBO J 18, 3064-3073
16. Kilger, E., Kieser, A., Baumann, M., and Hammerschmidt, W. (1998) Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor. EMBO J 17, 1700-1709
17. Kieser, A., Kilger, E., Gires, O., Ueffing, M., Kolch, W., and Hammerschmidt, W. (1997) Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade. EMBO J 16, 6478-6485