Angela Armento
| Surname | Armento |
| First name | Angela |
| Nationality | Italian |
| Present position and title | Postdoc, Dr. rer. nat |
Business address
Institute for Ophthalmic Research
University of Tübingen
Elfriede-Aulhorn-Strasse 7
D-72076 Tübingen,
Germany
Phone: +49 (0)7071 29-84953
Fax: +49 (0)7071 29-5777
E-mail: angela.armento@uni-tuebingen.de
Academic Education
| Year | Degree | University | Field of study |
|---|---|---|---|
2017 | PhD | University of Tuebingen | Cellular and Molecular Neuroscience |
2013 | Master degree | University of Parma | Medical, Pharmaceutical and Veterinary Biotechnologies |
2011 | Bachelor degree | University of Parma | Biotechnology |
Professional Experience
| Period | Institution | Position | Discipline |
|---|---|---|---|
2019-present | PostDoc | University of Tuebingen, Institute for Ophthalmic research | Complement system in age-related macular degeneration |
2017-2019 | PostDoc | University of Tuebingen, Institute for Ophthalmic research | Understing molecular drivers of Age-related macular degeneration |
2014-2017 | PhD | University of Tuebingen, Hertie Institute for Clinical Brain Research | The role of carboxypeptidase E in the “go or grow” hypothesis in glioblastoma” |
Awards
2013 | Erasmus Placement Scholarship: Training in Children Hospital, University of Tuebingen |
Travel Grants
2021 | Retinal Degeneration (RD) meeting and BrightFocus Fast track workshop Travel Award |
2015 | Prize for young scientist (travel) award 7th Mildred Scheel Cancer Conference |
Funded Grants
2021-2022 | Fortüne Junior Antrag nr. 2640-0-0. Impact of Complement Factor H Y402H polymorphism on RPE cells and AMD pathology. |
Selected Publications
Merle DA, Provenzano F, Jarboui MA, Kilger E, Clark SJ, Deleidi M, Armento A.* and Ueffing M.. mTOR inhibition via Rapamycin treatment partially reverts the deficit in energy metabolism caused by FH loss in RPE cells. Antioxidants. 2021. *co-last author
Armento A, Murali A, Marzi J, Arango-Gonzalez B, Kilger E, Clark SJ, et al. FH loss in RPE cells causes retinal degeneration in a human RPE-porcine retinal explant co-culture model. Biomolecules. 2021;11(11):1621.
Armento A, Schmidt TL, Sonntag I, Merle D, Jarboui MA, Kilger E, et al. CFH loss in human RPE cells leads to inflammation and complement system dysregulation via the NF-κB pathway. IJMS 2021.
Armento A, Ueffing M, Clark SJ. The complement system in age-related macular degeneration. Cell Mol Life Sci. 2021;78(10):4487-505.
Samardzija M, Corna A, Gomez-Sintes R, Jarboui MA, Armento A, Roger JE, et al. HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice. Cell Death Differ. 2021;28(4):1317-32.
Armento A, Honisch S, Panagiotakopoulou V, Sonntag I, Jacob A, Bolz S, et al. Loss of Complement Factor H impairs antioxidant capacity and energy metabolism of human RPE cells. Sci Rep. 2020;10(1):10320.
Armento A, Ehlers J, Schotterl S, Naumann U. Molecular Mechanisms of Glioma Cell Motility. In: De Vleeschouwer S, editor. Glioblastoma. Brisbane (AU)2017.
Armento A, Ilina EI, Kaoma T, Muller A, Vallar L, Niclou SP, et al. Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors. Int J Oncol. 2017;51(2):702-14.
Ilina EI, Armento A, Sanchez LG, Reichlmeir M, Braun Y, Penski C, et al. Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux. Oncotarget. 2017;8(40):67567-91.
Chiu M, Tardito S, Pillozzi S, Arcangeli A, Armento A, Uggeri J, et al. Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts. Br J Cancer. 2014;111(6):1159-67.